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[6] Pharmacokinetic Highlights: Oral Bioavailability: 38.4% (rats) [7] Half-Life: ~6.9 hours (oral), ~3.8 hours (IV) in rats Cmax: 2,252 ng/mL (oral, rats) Membrane Permeability: High (passive and active transport) Mechanism of Action 1
Abnormalities of one-carbon metabolism in psychiatric disorders: study of methionine adenosyltransferase kinetics and lipid composition of erythrocyte membranes Biol Psychiatry 1986
(PubMed) Leklem JE
